Oxford Nanopore Tech Revise: this new Duplex method for Q30 nanopore single molecule checks out, PromethION dos, and much more

Oxford Nanopore Tech Revise: this new Duplex method for Q30 nanopore single molecule checks out, PromethION dos, and much more

With the current equipment, profiles is capable of SNV reliability out-of 99

  • Within the a scientific update in the London area Calling 2021 fulfilling, Oxford Nanopore provided an introduction to recent program improves, and modal single-read precision off >99.3% having fun with “Q20+” chemistry and you may a selection of basecalling and you can library preparing solutions to match wide programs. The brand new Q20+ establishes are working in the hands out-of a tiny selection of developers and will be put-out on very early accessibility in the future
  • ‘Duplex’ was brought, a separate strategy that has shown single molecule reliability popular on Q30 (99.9%) in internal experiments, to be released in the near future

With the most recent devices, users is capable of SNV accuracy away from 99

  • The newest upcoming product tube comes with another type of device, the newest PromethION 2, helping larger access to highest productivity nanopore sequencing and you will ‘Outy’, an alternative ‘direction’ off sequencing which have multiple prospective positives.

Analysis production: A switch Roentgen&D purpose having Oxford Nanopore is to try to push optimised data output, in order that users is capable of rates-energetic studies at any scale. Several improvements to PromethION circulate structure was put out inside late 2020, and pursuing the an archive cracking PromethION run in , in which 10Tb of information are introduced on a single PromethION forty-eight work at, a recently available consumer number was number of 245Gb from a single disperse telephone. (suite…)

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